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Radiolabeling, whole-body single photon emission computed tomography/computed tomography imaging, and pharmacokinetics of carbon nanohorns in mice

In this work, we report that the biodistribution and excretion of carbon nanohorns (CNHs) in mice are dependent on their size and functionalization. Small-sized CNHs (30–50 nm; S-CNHs) and large-sized CNHs (80–100 nm; L-CNHs) were chemically functionalized and radiolabeled with [(111)In]-diethylenet...

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Detalles Bibliográficos
Autores principales: Zhang, Minfang, Jasim, Dhifaf A, Ménard-Moyon, Cécilia, Nunes, Antonio, Iijima, Sumio, Bianco, Alberto, Yudasaka, Masako, Kostarelos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965223/
https://www.ncbi.nlm.nih.gov/pubmed/27524892
http://dx.doi.org/10.2147/IJN.S103162