Postnatal muscle modification by myogenic factors modulates neuropathology and survival in an ALS mouse model

MyoD and myogenin are myogenic transcription factors preferentially expressed in adult fast and slow muscles, respectively. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which motor neuron loss is accompanied by muscle denervation and paralysis. Studies suggest that muscle p...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Kevin H.J., Franciosi, Sonia, Leavitt, Blair R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965267/
https://www.ncbi.nlm.nih.gov/pubmed/24346342
http://dx.doi.org/10.1038/ncomms3906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965267/
https://www.ncbi.nlm.nih.gov/pubmed/24346342
http://dx.doi.org/10.1038/ncomms3906

Ejemplares similares