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Nanoscale Imaging of RNA with Expansion Microscopy

The ability to image RNA identity and location with nanoscale precision in intact tissues is of great interest for defining cell types and states in normal and pathological biological settings. Here, we present a strategy for expansion microscopy (ExM) of RNA. We developed a small molecule linker th...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Wassie, Asmamaw T., Cote, Allison J., Sinha, Anubhav, Alon, Shahar, Asano, Shoh, Daugharthy, Evan R., Chang, Jae-Byum, Marblestone, Adam, Church, George M., Raj, Arjun, Boyden, Edward S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965288/
https://www.ncbi.nlm.nih.gov/pubmed/27376770
http://dx.doi.org/10.1038/nmeth.3899