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A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea

Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), plays a critical role in the pathogenesis of OSA-associated morbidities, especially in the cardiovascular and respiratory systems. Oxidative stress and inflammation induced by IH are suggested as main contributors of end-organ d...

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Detalles Bibliográficos
Autores principales: Campillo, Noelia, Jorba, Ignasi, Schaedel, Laura, Casals, Blai, Gozal, David, Farré, Ramon, Almendros, Isaac, Navajas, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965455/
https://www.ncbi.nlm.nih.gov/pubmed/27524971
http://dx.doi.org/10.3389/fphys.2016.00319