Cargando…

A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea

Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), plays a critical role in the pathogenesis of OSA-associated morbidities, especially in the cardiovascular and respiratory systems. Oxidative stress and inflammation induced by IH are suggested as main contributors of end-organ d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Campillo, Noelia, Jorba, Ignasi, Schaedel, Laura, Casals, Blai, Gozal, David, Farré, Ramon, Almendros, Isaac, Navajas, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965455/ https://www.ncbi.nlm.nih.gov/pubmed/27524971 http://dx.doi.org/10.3389/fphys.2016.00319

Ejemplares similares

Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study
por: Farré, Núria, et al.
Publicado: (2018)

Intermittent Hypoxia Severity in Animal Models of Sleep Apnea
por: Farré, Ramon, et al.
Publicado: (2018)

Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea
por: Menal, Maria José, et al.
Publicado: (2018)

Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea
por: Campillo, Noelia, et al.
Publicado: (2017)

Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea
por: Vilaseca, Antoni, et al.
Publicado: (2017)

Potential Role of Adult Stem Cells in Obstructive Sleep Apnea
por: Almendros, Isaac, et al.
Publicado: (2012)

Differential Oxygenation in Tumor Microenvironment Modulates Macrophage and Cancer Cell Crosstalk: Novel Experimental Setting and Proof of Concept
por: Campillo, Noelia, et al.
Publicado: (2019)

Chronic Sleep Fragmentation Mimicking Sleep Apnea Does Not Worsen Left-Ventricular Function in Healthy and Heart Failure Mice
por: Cabrera-Aguilera, Ignacio, et al.
Publicado: (2020)

Passive Stiffness of Left Ventricular Myocardial Tissue Is Reduced by Ovariectomy in a Post-menopause Mouse Model
por: Farré, Núria, et al.
Publicado: (2018)

Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea
por: Jurado, Alicia, et al.
Publicado: (2023)

Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea
por: Suarez-Giron, Monique C., et al.
Publicado: (2018)

Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity
por: Khalyfa, Abdelnaby, et al.
Publicado: (2021)

Experimental Models to Study End-Organ Morbidity in Sleep Apnea: Lessons Learned and Future Directions
por: Farré, Ramon, et al.
Publicado: (2022)

Heterogeneity of Melanoma Cell Responses to Sleep Apnea-Derived Plasma Exosomes and to Intermittent Hypoxia
por: Khalyfa, Abdelnaby, et al.
Publicado: (2021)

Gas Partial Pressure in Cultured Cells: Patho-Physiological Importance and Methodological Approaches
por: Farré, Ramon, et al.
Publicado: (2018)

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia
por: Cortese, Rene, et al.
Publicado: (2014)

Biomechanical Response of Lung Epithelial Cells to Iron Oxide and Titanium Dioxide Nanoparticles
por: Oliveira, Vinícius Rosa, et al.
Publicado: (2019)

Changes in oxygen partial pressure of brain tissue in an animal model of obstructive apnea
por: Almendros, Isaac, et al.
Publicado: (2010)

Baseline Stiffness Modulates the Non-Linear Response to Stretch of the Extracellular Matrix in Pulmonary Fibrosis
por: Júnior, Constança, et al.
Publicado: (2021)

Sleep apnea awakens cancer: A unifying immunological hypothesis
por: Gozal, David, et al.
Publicado: (2014)

Microarray-based analysis of plasma cirDNA epigenetic modification profiling in xenografted mice exposed to intermittent hypoxia
por: Cortese, Rene, et al.
Publicado: (2015)

Hydraulic fracture during epithelial stretching
por: Casares, Laura, et al.
Publicado: (2015)

Open access spreadsheet application for learning spontaneous breathing mechanics and mechanical ventilation
por: Navajas, Daniel, et al.
Publicado: (2021)

Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules
por: Khalyfa, Abdelnaby, et al.
Publicado: (2017)

Image-Based Method to Quantify Decellularization of Tissue Sections
por: Narciso, Maria, et al.
Publicado: (2021)

Alternative Procedure to Individual Nasal Pressure Titration for Sleep Apnea
por: Farré, Ramon, et al.
Publicado: (2021)

Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea
por: Nair, Deepti, et al.
Publicado: (2011)

Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea
por: Dayyat, Ehab A, et al.
Publicado: (2012)

Measuring ventral nerve cord stiffness in live flat-dissected Drosophila embryos by atomic force microscopy
por: Karkali, Katerina, et al.
Publicado: (2022)

Cell reorientation under cyclic stretching
por: Livne, Ariel, et al.
Publicado: (2014)

Intermittent hypoxia mimicking obstructive sleep apnea aggravates early brain injury following ICH via neuroinflammation and apoptosis
por: Fei, Wenjing, et al.
Publicado: (2021)

Sleep Apnoea Adverse Effects on Cancer: True, False, or Too Many Confounders?
por: Gozal, David, et al.
Publicado: (2020)

Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ
por: Nonaka, Paula N., et al.
Publicado: (2016)

Novel Decellularization Method for Tissue Slices
por: Narciso, Maria, et al.
Publicado: (2022)

A Mouse Model Suggests That Heart Failure and Its Common Comorbidity Sleep Fragmentation Have No Synergistic Impacts on the Gut Microbiome
por: Khannous-Lleiffe, Olfat, et al.
Publicado: (2021)

Aortic remodelling induced by obstructive apneas is normalized with mesenchymal stem cells infusion
por: Rubies, Cira, et al.
Publicado: (2019)

Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36
por: Cortese, Rene, et al.
Publicado: (2017)

Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells
por: Ramos, Pablo, et al.
Publicado: (2014)

Development of a physiomimetic model of acute respiratory distress syndrome by using ECM hydrogels and organ-on-a-chip devices
por: Marhuenda, Esther, et al.
Publicado: (2022)

Commentary: Intermittent Hypoxia Severity in Animal Models of Sleep Apnea
por: Jun, Jonathan C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ur8hilnj3db8m78kddq87igfqg