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Topical CpG Oligodeoxynucleotide Adjuvant Enhances the Adaptive Immune Response against Influenza A Infections

Current influenza vaccines generate humoral immunity, targeting highly variable epitopes and thus fail to achieve long-term protection. T cells recognize and respond to several highly conserved epitopes across influenza serotypes. A strategy of raising strong cytotoxic T cell memory responses to epi...

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Detalles Bibliográficos
Autores principales: Cheng, Wing Ki, Plumb, Adam William, Lai, Jacqueline Cheuk-Yan, Abraham, Ninan, Dutz, Jan Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965457/
https://www.ncbi.nlm.nih.gov/pubmed/27524984
http://dx.doi.org/10.3389/fimmu.2016.00284