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Lack of pharmacokinetic drug–drug interaction between ramucirumab and paclitaxel in a phase II study of patients with advanced malignant solid tumors

PURPOSE: The objective of this phase II study was to evaluate pharmacokinetic interaction potential between ramucirumab and paclitaxel in patients with advanced cancer. METHODS: This study was designed to assess 2-way pharmacokinetic drug–drug interactions between ramucirumab and paclitaxel. Twenty-...

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Detalles Bibliográficos
Autores principales: Chow, Laura Q. M., Smith, David C., Tan, Antoinette R., Denlinger, Crystal S., Wang, Ding, Shepard, Dale R., Chaudhary, Archana, Lin, Yong, Gao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965482/
https://www.ncbi.nlm.nih.gov/pubmed/27379498
http://dx.doi.org/10.1007/s00280-016-3098-3