Population pharmacokinetics of bevacizumab in cancer patients with external validation

BACKGROUND: Bevacizumab is approved for various cancers. This analysis aimed to comprehensively evaluate bevacizumab pharmacokinetics and the influence of patient variables on bevacizumab pharmacokinetics. METHODS: Rich and sparse bevacizumab serum concentrations were collected from Phase I through...

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Detalles Bibliográficos
Autores principales: Han, Kelong, Peyret, Thomas, Marchand, Mathilde, Quartino, Angelica, Gosselin, Nathalie H., Girish, Sandhya, Allison, David E., Jin, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965493/
https://www.ncbi.nlm.nih.gov/pubmed/27329360
http://dx.doi.org/10.1007/s00280-016-3079-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965493/
https://www.ncbi.nlm.nih.gov/pubmed/27329360
http://dx.doi.org/10.1007/s00280-016-3079-6

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