Cargando…

Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease

BACKGROUND: Dysfunctions of the ubiquitin proteasome system (UPS), including the highly abundant neuronal enzyme ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), and autophagy-related changes (lysosomal degradation) are implicated in several neurodegenerative disorders including Alzheimer's d...

Descripción completa

Detalles Bibliográficos
Autores principales: Öhrfelt, Annika, Johansson, Per, Wallin, Anders, Andreasson, Ulf, Zetterberg, Henrik, Blennow, Kaj, Svensson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965532/
https://www.ncbi.nlm.nih.gov/pubmed/27504117
http://dx.doi.org/10.1159/000447239