Conformational Selection and Submillisecond Dynamics of the Ligand-binding Domain of the N-Methyl-d-aspartate Receptor

The N-methyl-d-aspartate (NMDA) receptors are heteromeric non-selective cation channels that require the binding of glycine and glutamate for gating. Based on crystal structures, the mechanism of partial agonism at the glycine-binding site is thought to be mediated by a shift in the conformational e...

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Detalles Bibliográficos
Autores principales: Dolino, Drew M., Rezaei Adariani, Soheila, Shaikh, Sana A., Jayaraman, Vasanthi, Sanabria, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965566/
https://www.ncbi.nlm.nih.gov/pubmed/27226581
http://dx.doi.org/10.1074/jbc.M116.721274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965566/
https://www.ncbi.nlm.nih.gov/pubmed/27226581
http://dx.doi.org/10.1074/jbc.M116.721274

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