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A novel approach for multi-SNP GWAS and its application in Alzheimer’s disease

BACKGROUND: Genome-wide association studies (GWAS) have effectively identified genetic factors for many diseases. Many diseases, including Alzheimer’s disease (AD), have epistatic causes, requiring more sophisticated analyses to identify groups of variants which together affect phenotype. RESULTS: B...

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Detalles Bibliográficos
Autores principales: Bodily, Paul M., Fujimoto, M. Stanley, Page, Justin T., Clement, Mark J., Ebbert, Mark T. W., Ridge, Perry G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965706/
https://www.ncbi.nlm.nih.gov/pubmed/27453991
http://dx.doi.org/10.1186/s12859-016-1093-7