Diabetes Stimulates Osteoclastogenesis by Acidosis-Induced Activation of Transient Receptor Potential Cation Channels

Patients with type 1 diabetes have lower bone mineral density and higher risk of fractures. The role of osteoblasts in diabetes-related osteoporosis is well acknowledged whereas the role of osteoclasts (OCLs) is still unclear. We hypothesize that OCLs participate in pathological bone remodeling. We...

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Detalles Bibliográficos
Autores principales: Reni, Carlotta, Mangialardi, Giuseppe, Meloni, Marco, Madeddu, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965751/
https://www.ncbi.nlm.nih.gov/pubmed/27468810
http://dx.doi.org/10.1038/srep30639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965751/
https://www.ncbi.nlm.nih.gov/pubmed/27468810
http://dx.doi.org/10.1038/srep30639

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