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Trophoblastic debris modifies endothelial cell transcriptome in vitro: a mechanism by which fetal cells might control maternal responses to pregnancy

The mechanisms by which the fetus induces maternal physiological adaptations to pregnancy are unclear. Cellular debris, shed from the placental syncytiotrophoblast into the maternal blood and phagocytosed by maternal endothelial and immune cells, may be one of these mechanisms. Here we show that tro...

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Detalles Bibliográficos
Autores principales: Wei, J., Lau, S. Y., Blenkiron, C., Chen, Q., James, J. L., Kleffmann, T., Wise, M., Stone, P. R., Chamley, L. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965770/
https://www.ncbi.nlm.nih.gov/pubmed/27468655
http://dx.doi.org/10.1038/srep30632