In-column ATR-FTIR spectroscopy to monitor affinity chromatography purification of monoclonal antibodies

In recent years many monoclonal antibodies (mAb) have entered the biotherapeutics market, offering new treatments for chronic and life-threatening diseases. Protein A resin captures monoclonal antibody (mAb) effectively, but the binding capacity decays over repeated purification cycles. On an indust...

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Detalles Bibliográficos
Autores principales: Boulet-Audet, Maxime, Kazarian, Sergei G., Byrne, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965771/
https://www.ncbi.nlm.nih.gov/pubmed/27470880
http://dx.doi.org/10.1038/srep30526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965771/
https://www.ncbi.nlm.nih.gov/pubmed/27470880
http://dx.doi.org/10.1038/srep30526

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