Cargando…

In-column ATR-FTIR spectroscopy to monitor affinity chromatography purification of monoclonal antibodies

In recent years many monoclonal antibodies (mAb) have entered the biotherapeutics market, offering new treatments for chronic and life-threatening diseases. Protein A resin captures monoclonal antibody (mAb) effectively, but the binding capacity decays over repeated purification cycles. On an indust...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boulet-Audet, Maxime, Kazarian, Sergei G., Byrne, Bernadette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965771/ https://www.ncbi.nlm.nih.gov/pubmed/27470880 http://dx.doi.org/10.1038/srep30526

Ejemplares similares

Cleaning-in-place of immunoaffinity resins monitored by in situ ATR-FTIR spectroscopy
por: Boulet-Audet, Maxime, et al.
Publicado: (2015)

Insight into purification of monoclonal antibodies in industrial columns via studies of Protein A binding capacity by in situ ATR-FTIR spectroscopy
por: Beattie, James W., et al.
Publicado: (2021)

ATR-FTIR spectroscopy and spectroscopic imaging for the analysis of biopharmaceuticals
por: Tiernan, Hannah, et al.
Publicado: (2020)

High-Throughput Thermal Stability Analysis of a Monoclonal Antibody by Attenuated Total Reflection FT-IR Spectroscopic Imaging
por: Boulet-Audet, Maxime, et al.
Publicado: (2014)

ATR-FTIR spectroscopy and spectroscopic imaging to investigate the behaviour of proteins subjected to freeze–thaw cycles in droplets, wells, and under flow
por: Tiernan, Hannah, et al.
Publicado: (2021)

Time-Resolved ATR–FTIR Spectroscopy and Macro ATR–FTIR Spectroscopic Imaging of Inorganic Treatments for Stone Conservation
por: Possenti, Elena, et al.
Publicado: (2021)

Advances in ATR-FTIR Spectroscopic Imaging for the Analysis of Tablet Dissolution and Drug Release
por: van Haaren, Céline, et al.
Publicado: (2023)

Novel Approaches to In-Situ ATR-FTIR Spectroscopy and Spectroscopic Imaging for Real-Time Simultaneous Monitoring Curing Reaction and Diffusion of the Curing Agent at Rubber Nanocomposite Surface
por: Muroga, Shun, et al.
Publicado: (2021)

Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy
por: Krüger, Annika, et al.
Publicado: (2020)

Diagnosis of Lung Cancer by ATR-FTIR Spectroscopy and Chemometrics
por: Yang, Xien, et al.
Publicado: (2021)

ATR–FTIR Spectroscopy, HPLC Chromatography, and Multivariate Analysis for Controlling Bee Pollen Quality in Some Algerian Regions
por: Zeghoud, Soumeia, et al.
Publicado: (2021)

Urinalysis of individuals with renal hyperfiltration using ATR-FTIR spectroscopy
por: Kurultak, İlhan, et al.
Publicado: (2022)

Causes of Industrial Protein A Column Degradation, Explored Using Raman Spectroscopy
por: Beattie, James W., et al.
Publicado: (2022)

Monitoring of methylglyoxal/indole interaction by ATR-FTIR spectroscopy and qTOF/MS/MS analysis
por: Ghassem Zadeh, Raheleh, et al.
Publicado: (2020)

Insight into the effects of moisture and layer build-up on the formation of lead soaps using micro-ATR-FTIR spectroscopic imaging of complex painted stratigraphies
por: Possenti, Elena, et al.
Publicado: (2020)

Coupling Isotachophoresis with Affinity Chromatography for Rapid and Selective Purification with High Column Utilization, Part 1: Theory
por: Shkolnikov, Viktor, et al.
Publicado: (2014)

Application of Multivariable Analysis and FTIR-ATR Spectroscopy to the Prediction of Properties in Campeche Honey
por: Anguebes, Francisco, et al.
Publicado: (2016)

On the Protein Fibrillation Pathway: Oligomer Intermediates Detection Using ATR-FTIR Spectroscopy
por: Milošević, Jelica, et al.
Publicado: (2021)

FTIR Photoacoustic and ATR Spectroscopies of Soils with Aggregate Size Fractionation by Dry Sieving
por: Krivoshein, Petr K., et al.
Publicado: (2022)

Detection of breast cancer by ATR-FTIR spectroscopy using artificial neural networks
por: Tomas, Rock Christian, et al.
Publicado: (2022)

Know your enemy: Application of ATR-FTIR spectroscopy to invasive species control
por: Holden, Claire Anne, et al.
Publicado: (2022)

Highly Efficient Use of Infrared Spectroscopy (ATR-FTIR) to Identify Aphid Species
por: Durak, Roma, et al.
Publicado: (2022)

Coupling Isotachophoresis with Affinity Chromatography for Rapid and Selective Purification with High Column Utilization, Part 2: Experimental Study
por: Shkolnikov, Viktor, et al.
Publicado: (2014)

Purification of pituitary autoantigen by column liquid chromatography and chromatofocusing
por: Gut, Paweł, et al.
Publicado: (2014)

Fast quantitative determination of microbial rhamnolipids from cultivation broths by ATR-FTIR Spectroscopy
por: Leitermann, Frank, et al.
Publicado: (2008)

Sorption of phosphate onto mesoporous γ-alumina studied with in-situ ATR-FTIR spectroscopy
por: Zheng, Ting-Ting, et al.
Publicado: (2012)

Application of FTIR-ATR Spectroscopy to Determine the Extent of Lipid Peroxidation in Plasma during Haemodialysis
por: Oleszko, Adam, et al.
Publicado: (2015)

Pleurotus Mushrooms Content in Glucans and Ergosterol Assessed by ATR-FTIR Spectroscopy and Multivariate Analysis
por: Bekiaris, Georgios, et al.
Publicado: (2020)

Influence of the Sample Preparation Method in Discriminating Candida spp. Using ATR-FTIR Spectroscopy
por: Pebotuwa, Savithri, et al.
Publicado: (2020)

Classification of Unifloral Honeys from SARDINIA (Italy) by ATR-FTIR Spectroscopy and Random Forest
por: Ciulu, Marco, et al.
Publicado: (2020)

Correction: Know your enemy: Application of ATR-FTIR spectroscopy to invasive species control
por: Holden, Claire Anne, et al.
Publicado: (2022)

ATR-FTIR spectroscopy of plasma supported by multivariate analysis discriminates multiple sclerosis disease
por: Crocco, Maria Caterina, et al.
Publicado: (2023)

ATR-FTIR Biosensors for Antibody Detection and Analysis
por: Suys, Olivier, et al.
Publicado: (2022)

Production and Purification of Streptokinase by Protected Affinity Chromatography
por: Babashamsi, Mohammad, et al.
Publicado: (2009)

ATR-FTIR Spectroscopy for the Assessment of Biochemical Changes in Skin Due to Cutaneous Squamous Cell Carcinoma
por: Lima, Cássio A., et al.
Publicado: (2015)

Determination of Dental Adhesive Composition throughout Solvent Drying and Polymerization Using ATR–FTIR Spectroscopy
por: Almusa, Arwa, et al.
Publicado: (2021)

An indirect analytical approach based on ATR-FTIR spectroscopy for determining the FFA content in vegetable oils
por: Dong, Yaoyao, et al.
Publicado: (2020)

Structural Rearrangements of Carbonic Anhydrase Entrapped in Sol-Gel Magnetite Determined by ATR–FTIR Spectroscopy
por: Ivanovski, Vladimir, et al.
Publicado: (2022)

Fast and Deep Diagnosis Using Blood-Based ATR-FTIR Spectroscopy for Digestive Tract Cancers
por: Guo, Shanshan, et al.
Publicado: (2022)

Comparison of DNA preservation and ATR-FTIR spectroscopy indices of cortical and trabecular bone of metacarpals and metatarsals
por: Leskovar, Tamara, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dr9hhkrg4ni17fcendc5p79oqg