T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice

SKAP1 is an immune cell adaptor that couples the T-cell receptor with the ‘inside-out’ signalling pathway for LFA-1 mediated adhesion in T-cells. A connection of SKAP1 to the regulation of an autoimmune disorder has not previously been reported. In this study, we show that Skap1-deficient (skap1-/-)...

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Detalles Bibliográficos
Autores principales: Smith, Xin, Taylor, Alison, Rudd, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965781/
https://www.ncbi.nlm.nih.gov/pubmed/27181093
http://dx.doi.org/10.1016/j.imlet.2016.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965781/
https://www.ncbi.nlm.nih.gov/pubmed/27181093
http://dx.doi.org/10.1016/j.imlet.2016.04.007

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