In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma

[Image: see text] The ability to activate drugs only at desired locations avoiding systemic immunosuppression and other dose limiting toxicities is highly desirable. Here we present a new approach, named local drug activation, that uses bioorthogonal chemistry to concentrate and activate systemic sm...

Descripción completa

Detalles Bibliográficos
Autores principales: Mejia Oneto, Jose M., Khan, Irfan, Seebald, Leah, Royzen, Maksim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965853/
https://www.ncbi.nlm.nih.gov/pubmed/27504494
http://dx.doi.org/10.1021/acscentsci.6b00150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965853/
https://www.ncbi.nlm.nih.gov/pubmed/27504494
http://dx.doi.org/10.1021/acscentsci.6b00150

Ejemplares similares