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Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System

[Image: see text] Multisite phosphorylation is a common pathway to regulate protein function, activity, and interaction pattern in vivo, but routine biochemical analysis is often insufficient to identify the number and order of individual phosphorylation reactions and their mechanistic impact on the...

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Detalles Bibliográficos
Autores principales: Lössl, Philip, Brunner, Andrea M., Liu, Fan, Leney, Aneika C., Yamashita, Masami, Scheltema, Richard A., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965854/
https://www.ncbi.nlm.nih.gov/pubmed/27504491
http://dx.doi.org/10.1021/acscentsci.6b00053