Mechanism of artemisinin resistance for malaria PfATP6 L263 mutations and discovering potential antimalarials: An integrated computational approach

Artemisinin resistance in Plasmodium falciparum threatens global efforts in the elimination or eradication of malaria. Several studies have associated mutations in the PfATP6 gene in conjunction with artemisinin resistance, but the underlying molecular mechanism of the resistance remains unexplored....

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Detalles Bibliográficos
Autores principales: N., Nagasundaram, C., George Priya Doss, Chakraborty, Chiranjib, V., Karthick, D., Thirumal Kumar, V., Balaji, R., Siva, Lu, Aiping, Ge, Zhang, Zhu, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965867/
https://www.ncbi.nlm.nih.gov/pubmed/27471101
http://dx.doi.org/10.1038/srep30106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965867/
https://www.ncbi.nlm.nih.gov/pubmed/27471101
http://dx.doi.org/10.1038/srep30106

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