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Pervasive isoform‐specific translational regulation via alternative transcription start sites in mammals

Transcription initiated at alternative sites can produce mRNA isoforms with different 5ʹUTRs, which are potentially subjected to differential translational regulation. However, the prevalence of such isoform‐specific translational control across mammalian genomes is currently unknown. By combining p...

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Detalles Bibliográficos
Autores principales: Wang, Xi, Hou, Jingyi, Quedenau, Claudia, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965872/
https://www.ncbi.nlm.nih.gov/pubmed/27430939
http://dx.doi.org/10.15252/msb.20166941