Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation

T‐cell receptor (TCR) signaling is essential for the function of T cells and negatively regulated by the E3 ubiquitin–protein ligases CBL and CBLB. Here, we combined mouse genetics and affinity purification coupled to quantitative mass spectrometry to monitor the dynamics of the CBL and CBLB signali...

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Detalles Bibliográficos
Autores principales: Voisinne, Guillaume, García‐Blesa, Antonio, Chaoui, Karima, Fiore, Frédéric, Bergot, Elise, Girard, Laura, Malissen, Marie, Burlet‐Schiltz, Odile, Gonzalez de Peredo, Anne, Malissen, Bernard, Roncagalli, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965873/
https://www.ncbi.nlm.nih.gov/pubmed/27474268
http://dx.doi.org/10.15252/msb.20166837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965873/
https://www.ncbi.nlm.nih.gov/pubmed/27474268
http://dx.doi.org/10.15252/msb.20166837

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