Evidence for sex-specific genetic architectures across a spectrum of human complex traits

BACKGROUND: Sex differences are a common feature of human traits; however, the role sex determination plays in human genetic variation remains unclear. The presence of gene-by-sex (GxS) interactions implies that trait genetic architecture differs between men and women. Here, we show that GxS interac...

Descripción completa

Detalles Bibliográficos
Autores principales: Rawlik, Konrad, Canela-Xandri, Oriol, Tenesa, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965887/
https://www.ncbi.nlm.nih.gov/pubmed/27473438
http://dx.doi.org/10.1186/s13059-016-1025-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965887/
https://www.ncbi.nlm.nih.gov/pubmed/27473438
http://dx.doi.org/10.1186/s13059-016-1025-x

Ejemplares similares