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Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice

BACKGROUND: GPR120 (FFAR4) is a G-protein coupled receptor implicated in the development of obesity and the antiinflammatory and insulin-sensitizing effects of omega-3 (ω-3) polyunsaturated fatty acids. Increasing central ω-3 polyunsaturated fatty acid levels has been shown to have both anorectic an...

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Detalles Bibliográficos
Autores principales: Auguste, Stéphanie, Fisette, Alexandre, Fernandes, Maria F., Hryhorczuk, Cécile, Poitout, Vincent, Alquier, Thierry, Fulton, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966276/
https://www.ncbi.nlm.nih.gov/pubmed/26888796
http://dx.doi.org/10.1093/ijnp/pyw014