Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation

The pH-dependent antigen binding antibody, termed a recycling antibody, has recently been reported as an attractive type of second-generation engineered therapeutic antibody. A recycling antibody can dissociate antigen in the acidic endosome, and thus bind to its antigen multiple times. As a consequ...

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Detalles Bibliográficos
Autores principales: Hironiwa, N, Ishii, S, Kadono, S, Iwayanagi, Y, Mimoto, F, Habu, K, Igawa, T, Hattori, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966519/
https://www.ncbi.nlm.nih.gov/pubmed/26496237
http://dx.doi.org/10.1080/19420862.2015.1110660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966519/
https://www.ncbi.nlm.nih.gov/pubmed/26496237
http://dx.doi.org/10.1080/19420862.2015.1110660

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