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Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation
The pH-dependent antigen binding antibody, termed a recycling antibody, has recently been reported as an attractive type of second-generation engineered therapeutic antibody. A recycling antibody can dissociate antigen in the acidic endosome, and thus bind to its antigen multiple times. As a consequ...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966519/ https://www.ncbi.nlm.nih.gov/pubmed/26496237 http://dx.doi.org/10.1080/19420862.2015.1110660 |