Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

Transforming growth factor (TGF)β levels are elevated in, and drive the progression of, numerous disease states such as advanced metastatic cancer and systemic and ocular fibrosis. There are 3 main isoforms, TGFβ1, 2, and 3. As multiple TGFβ isoforms are involved in disease processes, maximal therap...

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Detalles Bibliográficos
Autores principales: Bedinger, Daniel, Lao, Llewelyn, Khan, Shireen, Lee, Steve, Takeuchi, Toshihiko, Mirza, Amer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966579/
https://www.ncbi.nlm.nih.gov/pubmed/26563652
http://dx.doi.org/10.1080/19420862.2015.1115166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966579/
https://www.ncbi.nlm.nih.gov/pubmed/26563652
http://dx.doi.org/10.1080/19420862.2015.1115166

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