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PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling

BACKGROUND: Peptidylarginine deiminase (PAD) post-translationally converts arginine residues to citrulline residues. Recent studies have suggested that PADI2 (PAD isoform 2), a member of the PAD family, is involved in the tumorigenic process of some tumors, especially breast cancer. However, little...

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Detalles Bibliográficos
Autores principales: Wang, Huifeng, Xu, Bing, Zhang, Xiaoqian, Zheng, Yabing, Zhao, Yan, Chang, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966586/
https://www.ncbi.nlm.nih.gov/pubmed/27478411
http://dx.doi.org/10.1186/s12935-016-0335-0