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Rapid genotype imputation from sequence without reference panels

Inexpensive genotyping methods are essential for genetic studies requiring large sample sizes. In human studies, array-based microarrays and high-density haplotype reference panels allow efficient genotype imputation for this purpose. However, these resources are typically unavailable in non-human s...

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Detalles Bibliográficos
Autores principales: Davies, Robert W., Flint, Jonathan, Myers, Simon, Mott, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966640/
https://www.ncbi.nlm.nih.gov/pubmed/27376236
http://dx.doi.org/10.1038/ng.3594