Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

Two bottlenecks impeding the genetic analysis of complex traits in rodents are access to mapping populations able to deliver gene-level mapping resolution, and the need for population specific genotyping arrays and haplotype reference panels. Here we combine low coverage sequencing (0.15X) with a no...

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Detalles Bibliográficos
Autores principales: Nicod, Jérôme, Davies, Robert W., Cai, Na, Hassett, Carl, Goodstadt, Leo, Cosgrove, Cormac, Yee, Benjamin K, Lionikaite, Vikte, McIntyre, Rebecca E, Remme, Carol Ann, Lodder, Elisabeth M., Gregory, Jennifer S., Hough, Tertius, Joynson, Russell, Phelps, Hayley, Nell, Barbara, Rowe, Clare, Wood, Joe, Walling, Alison, Bopp, Nasrin, Bhomra, Amarjit, Hernandez-Pliego, Polinka, Callebert, Jacques, Aspden, Richard M., Talbot, Nick P, Robbins, Peter A, Harrison, Mark, Fray, Martin, Launay, Jean-Marie, Pinto, Yigal M., Blizard, David A., Bezzina, Connie R., Adams, David J, Franken, Paul, Weaver, Tom, Wells, Sara, Brown, Steve DM, Potter, Paul K, Klenerman, Paul, Lionikas, Arimantas, Mott, Richard, Flint, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966644/
https://www.ncbi.nlm.nih.gov/pubmed/27376238
http://dx.doi.org/10.1038/ng.3595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966644/
https://www.ncbi.nlm.nih.gov/pubmed/27376238
http://dx.doi.org/10.1038/ng.3595

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