Paclitaxel plus valproic acid versus paclitaxel alone as second- or third-line therapy for advanced gastric cancer: a randomized Phase II trial

BACKGROUND: Weekly paclitaxel (wPTX) is the preferred second-line chemotherapy for gastric cancer in Japan. Histone deacetylase inhibitors have been shown to decrease proliferation through cell-cycle arrest, differentiation, and apoptosis in gastric cancer cells. One histone deacetylase inhibitor, v...

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Detalles Bibliográficos
Autores principales: Fushida, Sachio, Kinoshita, Jun, Kaji, Masahide, Oyama, Katsunobu, Hirono, Yasuo, Tsukada, Tomoya, Fujimura, Takashi, Ohta, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966651/
https://www.ncbi.nlm.nih.gov/pubmed/27524882
http://dx.doi.org/10.2147/DDDT.S110425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966651/
https://www.ncbi.nlm.nih.gov/pubmed/27524882
http://dx.doi.org/10.2147/DDDT.S110425

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