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Paclitaxel plus valproic acid versus paclitaxel alone as second- or third-line therapy for advanced gastric cancer: a randomized Phase II trial

BACKGROUND: Weekly paclitaxel (wPTX) is the preferred second-line chemotherapy for gastric cancer in Japan. Histone deacetylase inhibitors have been shown to decrease proliferation through cell-cycle arrest, differentiation, and apoptosis in gastric cancer cells. One histone deacetylase inhibitor, v...

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Detalles Bibliográficos
Autores principales:	Fushida, Sachio, Kinoshita, Jun, Kaji, Masahide, Oyama, Katsunobu, Hirono, Yasuo, Tsukada, Tomoya, Fujimura, Takashi, Ohta, Tetsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966651/ https://www.ncbi.nlm.nih.gov/pubmed/27524882 http://dx.doi.org/10.2147/DDDT.S110425

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