Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

Functionally altered biological mechanisms arising from disease-associated polymorphisms, remain difficult to characterise when those variants are intergenic, or, fall between genes. We sought to identify shared downstream mechanisms by which inter- and intragenic single-nucleotide polymorphisms (SN...

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Detalles Bibliográficos
Autores principales: Li, Haiquan, Achour, Ikbel, Bastarache, Lisa, Berghout, Joanne, Gardeux, Vincent, Li, Jianrong, Lee, Younghee, Pesce, Lorenzo, Yang, Xinan, Ramos, Kenneth S, Foster, Ian, Denny, Joshua C, Moore, Jason H, Lussier, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966659/
https://www.ncbi.nlm.nih.gov/pubmed/27482468
http://dx.doi.org/10.1038/npjgenmed.2016.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966659/
https://www.ncbi.nlm.nih.gov/pubmed/27482468
http://dx.doi.org/10.1038/npjgenmed.2016.6

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