Continuous synthesis of drug-loaded nanoparticles using microchannel emulsification and numerical modeling: effect of passive mixing

By using interdigital microfluidic reactors, monodisperse poly(d,l lactic-co-glycolic acid) nanoparticles (NPs) can be produced in a continuous manner and at a large scale (~10 g/h). An optimized synthesis protocol was obtained by selecting the appropriated passive mixer and fluid flow conditions to...

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Detalles Bibliográficos
Autores principales: Ortiz de Solorzano, Isabel, Uson, Laura, Larrea, Ane, Miana, Mario, Sebastian, Victor, Arruebo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966691/
https://www.ncbi.nlm.nih.gov/pubmed/27524896
http://dx.doi.org/10.2147/IJN.S108812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966691/
https://www.ncbi.nlm.nih.gov/pubmed/27524896
http://dx.doi.org/10.2147/IJN.S108812

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