Fabrication and biological evaluation of chitosan coated hyaluronic acid-docetaxel conjugate nanoparticles in CD44(+) cancer cells

BACKGROUND: Hyaluronic acid (HA) has been used for target-specific drug delivery because of strong affinity to CD44, a marker in which overexpressed in cancer cells and cancer stem cells. Conjugation of HA to the cytotoxic agents via active targeting can improve efficacy, biodistribution, and water...

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Detalles Bibliográficos
Autores principales: Shabani Ravari, Nazanin, Goodarzi, Navid, Alvandifar, Farhad, Amini, Mohsen, Souri, Effat, Khoshayand, Mohammad Reza, Hadavand Mirzaie, Zahra, Atyabi, Fatemeh, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966701/
https://www.ncbi.nlm.nih.gov/pubmed/27473554
http://dx.doi.org/10.1186/s40199-016-0160-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966701/
https://www.ncbi.nlm.nih.gov/pubmed/27473554
http://dx.doi.org/10.1186/s40199-016-0160-y

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