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CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

The β common-signaling cytokines interleukin (IL)-3, granulocyte-macrophage colony stimulating factor (GM-CSF) and IL-5 stimulate pro-inflammatory activities of haematopoietic cells via a receptor complex incorporating cytokine-specific α and shared β common (β(c), CD131) receptor. Evidence from ani...

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Detalles Bibliográficos
Autores principales: Panousis, Con, Dhagat, Urmi, Edwards, Kirsten M., Rayzman, Veronika, Hardy, Matthew P., Braley, Hal, Gauvreau, Gail M., Hercus, Timothy R., Smith, Steven, Sehmi, Roma, McMillan, Laura, Dottore, Mara, McClure, Barbara J., Fabri, Louis J., Vairo, Gino, Lopez, Angel F, Parker, Michael W., Nash, Andrew D., Wilson, Nicholas J., Wilson, Michael J., Owczarek, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966837/
https://www.ncbi.nlm.nih.gov/pubmed/26651396
http://dx.doi.org/10.1080/19420862.2015.1119352