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Secukinumab, a novel anti–IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity

Secukinumab is a human monoclonal antibody that selectively targets interleukin-17A and has been demonstrated to be highly efficacious in the treatment of moderate to severe plaque psoriasis, starting at early time points, with a sustained effect and a favorable safety profile. Biotherapeutics—inclu...

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Detalles Bibliográficos
Autores principales: Karle, Anette, Spindeldreher, Sebastian, Kolbinger, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966846/
https://www.ncbi.nlm.nih.gov/pubmed/26817498
http://dx.doi.org/10.1080/19420862.2015.1136761