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F-actin dismantling through a Redox-driven synergy between Mical and cofilin

Numerous cellular functions depend on actin filament (F-actin) disassembly. The best-characterized disassembly proteins, the ADF/cofilins/twinstar, sever filaments and recycle monomers to promote actin assembly. Cofilin is also a relatively weak actin disassembler, posing questions about mechanisms...

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Detalles Bibliográficos
Autores principales: Grintsevich, Elena E., Yesilyurt, Hunkar Gizem, Rich, Shannon K., Hung, Ruei-Jiun, Terman, Jonathan R., Reisler, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966907/
https://www.ncbi.nlm.nih.gov/pubmed/27454820
http://dx.doi.org/10.1038/ncb3390