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Revisiting the Heterogeneous IFN-γ Response of Bacille of Calmette-Guérin (BCG)-Revaccinated Healthy Volunteers in a Randomized Controlled Trial: Effect of the Body Mass Index and of the IFNG+874 A/T Polymorphism

In trials evaluating the immune responses to Bacille of Calmette-Guérin (BCG), the genetic background and the nutritional status are host-related factors that could affect the heterogeneity in these parameters. The IFNG+874 A/T (rs 62559044) polymorphism has been reported to influence the IFN-γ prod...

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Detalles Bibliográficos
Autores principales: Conceição, Elisabete L., Nascimento-Sampaio, Francisco S., Schwingel, Paulo A., Oliveira, Evelin S., Rocha, Michael S., Vieira, Igor, Mendes, Carlos M. C., Souza-Machado, Adelmir, Oliveira, Martha M., Barral-Netto, Manoel, Marinho, Jamocyr M., Barbosa, Theolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966948/
https://www.ncbi.nlm.nih.gov/pubmed/27472280
http://dx.doi.org/10.1371/journal.pone.0160149