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Revisiting the Heterogeneous IFN-γ Response of Bacille of Calmette-Guérin (BCG)-Revaccinated Healthy Volunteers in a Randomized Controlled Trial: Effect of the Body Mass Index and of the IFNG+874 A/T Polymorphism
In trials evaluating the immune responses to Bacille of Calmette-Guérin (BCG), the genetic background and the nutritional status are host-related factors that could affect the heterogeneity in these parameters. The IFNG+874 A/T (rs 62559044) polymorphism has been reported to influence the IFN-γ prod...
Autores principales: | Conceição, Elisabete L., Nascimento-Sampaio, Francisco S., Schwingel, Paulo A., Oliveira, Evelin S., Rocha, Michael S., Vieira, Igor, Mendes, Carlos M. C., Souza-Machado, Adelmir, Oliveira, Martha M., Barral-Netto, Manoel, Marinho, Jamocyr M., Barbosa, Theolis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966948/ https://www.ncbi.nlm.nih.gov/pubmed/27472280 http://dx.doi.org/10.1371/journal.pone.0160149 |
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