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Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches

The bile salt export pump (BSEP, ABCB11) plays an essential role in the formation of bile. In hepatocytes, BSEP is localized within the apical (canalicular) membrane and a deficiency of canalicular BSEP function is associated with severe forms of cholestasis. Regulation of correct trafficking to the...

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Detalles Bibliográficos
Autores principales: Przybylla, Susanne, Stindt, Jan, Kleinschrodt, Diana, Schulte am Esch, Jan, Häussinger, Dieter, Keitel, Verena, Smits, Sander H., Schmitt, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966956/
https://www.ncbi.nlm.nih.gov/pubmed/27472061
http://dx.doi.org/10.1371/journal.pone.0159778