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Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches
The bile salt export pump (BSEP, ABCB11) plays an essential role in the formation of bile. In hepatocytes, BSEP is localized within the apical (canalicular) membrane and a deficiency of canalicular BSEP function is associated with severe forms of cholestasis. Regulation of correct trafficking to the...
Autores principales: | Przybylla, Susanne, Stindt, Jan, Kleinschrodt, Diana, Schulte am Esch, Jan, Häussinger, Dieter, Keitel, Verena, Smits, Sander H., Schmitt, Lutz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966956/ https://www.ncbi.nlm.nih.gov/pubmed/27472061 http://dx.doi.org/10.1371/journal.pone.0159778 |
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