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An Improved System for Generation of Diploid Cloned Porcine Embryos Using Induced Pluripotent Stem Cells Synchronized to Metaphase

Pigs provide outstanding models of human genetic diseases due to their striking similarities with human anatomy, physiology and genetics. Although transgenic pigs have been produced using genetically modified somatic cells and nuclear transfer (SCNT), the cloning efficiency was extremely low. Here,...

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Detalles Bibliográficos
Autores principales: Kim, Eunhye, Zheng, Zhong, Jeon, Yubyeol, Jin, Yong-Xun, Hwang, Seon-Ung, Cai, Lian, Lee, Chang-Kyu, Kim, Nam-Hyung, Hyun, Sang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966966/
https://www.ncbi.nlm.nih.gov/pubmed/27472781
http://dx.doi.org/10.1371/journal.pone.0160289