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An Improved System for Generation of Diploid Cloned Porcine Embryos Using Induced Pluripotent Stem Cells Synchronized to Metaphase
Pigs provide outstanding models of human genetic diseases due to their striking similarities with human anatomy, physiology and genetics. Although transgenic pigs have been produced using genetically modified somatic cells and nuclear transfer (SCNT), the cloning efficiency was extremely low. Here,...
Autores principales: | Kim, Eunhye, Zheng, Zhong, Jeon, Yubyeol, Jin, Yong-Xun, Hwang, Seon-Ung, Cai, Lian, Lee, Chang-Kyu, Kim, Nam-Hyung, Hyun, Sang-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966966/ https://www.ncbi.nlm.nih.gov/pubmed/27472781 http://dx.doi.org/10.1371/journal.pone.0160289 |
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