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Tetrahymena Poc1 ensures proper intertriplet microtubule linkages to maintain basal body integrity
Basal bodies comprise nine symmetric triplet microtubules that anchor forces produced by the asymmetric beat pattern of motile cilia. The ciliopathy protein Poc1 stabilizes basal bodies through an unknown mechanism. In poc1∆ cells, electron tomography reveals subtle defects in the organization of in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966981/ https://www.ncbi.nlm.nih.gov/pubmed/27251062 http://dx.doi.org/10.1091/mbc.E16-03-0165 |