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Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites

The Vps13 protein family is highly conserved in eukaryotic cells. Mutations in human VPS13 genes result in a variety of diseases, such as chorea acanthocytosis (ChAc), but the cellular functions of Vps13 proteins are not well defined. In yeast, there is a single VPS13 orthologue, which is required f...

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Detalles Bibliográficos
Autores principales: Park, Jae-Sook, Thorsness, Mary K., Policastro, Robert, McGoldrick, Luke L., Hollingsworth, Nancy M., Thorsness, Peter E., Neiman, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966984/
https://www.ncbi.nlm.nih.gov/pubmed/27280386
http://dx.doi.org/10.1091/mbc.E16-02-0112