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Receptor tyrosine kinase Met promotes cell survival via kinase-independent maintenance of integrin α3β1

Matrix adhesion via integrins is required for cell survival. Adhesion of epithelial cells to laminin via integrin α3β1 was previously shown to activate at least two independent survival pathways. First, integrin α3β1 is required for autophagy-induced cell survival after growth factor deprivation. Se...

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Detalles Bibliográficos
Autores principales: Tesfay, Lia, Schulz, Veronique V., Frank, Sander B., Lamb, Laura E., Miranti, Cindy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966988/
https://www.ncbi.nlm.nih.gov/pubmed/27307589
http://dx.doi.org/10.1091/mbc.E15-09-0649