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Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense

Trypanosoma brucei rhodesiense is one of the causative agents of human sleeping sickness, a fatal disease that is transmitted by tsetse flies and restricted to Sub-Saharan Africa. Here we investigate two independent lines of T. b. rhodesiense that have been selected with the drugs melarsoprol and pe...

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Detalles Bibliográficos
Autores principales: Graf, Fabrice E., Ludin, Philipp, Arquint, Christian, Schmidt, Remo S., Schaub, Nadia, Kunz Renggli, Christina, Munday, Jane C., Krezdorn, Jessica, Baker, Nicola, Horn, David, Balmer, Oliver, Caccone, Adalgisa, de Koning, Harry P., Mäser, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967103/
https://www.ncbi.nlm.nih.gov/pubmed/26973180
http://dx.doi.org/10.1007/s00018-016-2173-6