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Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass

Estrogens are important regulators of bone mass and their effects are mainly mediated via estrogen receptor (ER)α. Central ERα exerts an inhibitory role on bone mass. ERα is highly expressed in the arcuate (ARC) and the ventromedial (VMN) nuclei in the hypothalamus. To test whether ERα in proopiomel...

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Detalles Bibliográficos
Autores principales: Farman, H. H., Windahl, S. H., Westberg, L., Isaksson, H., Egecioglu, E., Schele, E., Ryberg, H., Jansson, J. O., Tuukkanen, J., Koskela, A., Xie, S. K., Hahner, L., Zehr, J., Clegg, D. J., Lagerquist, M. K., Ohlsson, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967117/
https://www.ncbi.nlm.nih.gov/pubmed/27254004
http://dx.doi.org/10.1210/en.2016-1181