The role of circulating thrombospondin-1 in patients with precapillary pulmonary hypertension

BACKGROUND: The vasoconstrictive protein TSP-1 is released from endothelial cells upon increased shear stress and hypoxia. Both conditions are prevalent in pulmonary hypertension (PH). TSP-1 damages the local microcirculation by disrupting pathways, which are essential for specific medical therapeut...

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Detalles Bibliográficos
Autores principales: Kaiser, Ralf, Frantz, Christian, Bals, Robert, Wilkens, Heinrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967340/
https://www.ncbi.nlm.nih.gov/pubmed/27473366
http://dx.doi.org/10.1186/s12931-016-0412-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967340/
https://www.ncbi.nlm.nih.gov/pubmed/27473366
http://dx.doi.org/10.1186/s12931-016-0412-x

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