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The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism

AIMS/HYPOTHESIS: Potentiation of glucose-induced insulin secretion is the main mechanism of exenatide (EXE) antidiabetic action, however, increased glucose utilization by peripheral tissues has been also reported. We here studied the effect of EXE on glucose uptake by skeletal muscle cells. METHODS:...

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Detalles Bibliográficos
Autores principales: Andreozzi, Francesco, Raciti, Gregory Alexander, Nigro, Cecilia, Mannino, Gaia Chiara, Procopio, Teresa, Davalli, Alberto M., Beguinot, Francesco, Sesti, Giorgio, Miele, Claudia, Folli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967343/
https://www.ncbi.nlm.nih.gov/pubmed/27473212
http://dx.doi.org/10.1186/s12967-016-0985-7